Zolpidem(Ambien)10Mg

Zolpidem(Ambien)10Mg for sale online in USA.Zolpidem, sold under the brand name Ambien among others, is a medication primarily used for the short-term treatment of sleeping problems.^[9][11] Guidelines recommend that it be used only after cognitive behavioral therapy for insomnia and behavioral changes, such as sleep hygiene, have been tried.^[12][13][14] It decreases the time to sleep onset by about fifteen minutes and at larger doses helps people stay asleep longer.^[6] It is taken by mouth and is available in conventional tablets, sublingual tablets, or oral spray.^[9]

Common side effects include daytime sleepiness, headache, nausea, and diarrhea.^[9] More severe side effects include memory problems and hallucinations.^[6] While flumazenil, a GABA_A–receptor antagonist, can reverse zolpidem’s effects, usually supportive care is all that is recommended in overdose.^[15]

Zolpidem is a nonbenzodiazepine or Z-drug which acts as a sedative and hypnotic.^[9][15] Zolpidem is a GABA_A receptor agonist of the imidazopyridine class.^[9] It works by increasing GABA effects in the central nervous system by binding to GABA_A receptors at the same location as benzodiazepines.^[9] It generally has a half-life of two to three hours.^[9] This, however, is increased in those with liver problems.^[9]

Zolpidem was approved for medical use in the United States in 1992.^[9][16] It became available as a generic medication in 2007.^[17] Zolpidem is a Schedule IV controlled substance under the Controlled Substances Act of 1970 (CSA).^[6][7] More than ten million prescriptions are filled each year in the United States, making it one of the most commonly used treatments for sleeping problems.^[18][19] In 2020, it was the 47th most commonly prescribed medication in the United States, with more than 14 million prescriptions.

Medical uses

Zolpidem is labeled for short-term (usually about two to six weeks) treatment of insomnia at the lowest possible dose.^[9][11] It may be used for both improving sleep onset, sleep onset latency, and staying asleep.^[6]

Guidelines from NICE, the European Sleep Research Society, and the American College of Physicians recommend

medication for insomnia (including possibly zolpidem) only as a

second line treatment after non-pharmacological treatment options have been tried (e.g. cognitive behavioral therapy for insomnia).^[12][13][14] This is based in part on a 2012 review which found that zolpidem’s effectiveness is nearly as much due to psychological effects as to the medication itself.